Expression of pendrin in benign and malignant human thyroid tissues
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چکیده
منابع مشابه
Expression of TRPC6 in benign and malignant human prostate tissues.
We investigated the expression of transient receptor potential canonical 6 (TRPC6) protein in benign and malignant human prostate tissues and in prostate cancer cell lines and the association with the stage, grade and androgen responsiveness of the tumors. Immunohistochemical techniques, Western blot and reverse transcription polymerase chain reaction (RT-PCR) were used to investigate TRPC6 exp...
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INTRODUCTION Different mechanisms for the expression of pendrin which is an apical iodide transporter have been reported in nodular thyroid tissues compared to normal thyroid. The aim of the present study was to determine the alterations of pendrin expression in nodular and surrounding non-nodular thyroid tissues and clarify the role of pendrin in the functional behaviour of nodular lesions. ...
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Background & Objective: Malignant breast tumors, which are one of the most important deadly cancers in women, like many other cancers, are proposed to be related to viruses etiologically. Proper management of breast carcinoma necessitates an identification of the etiological factors. Human Papillomavirus is considered to have an etiological role in breast carcinoma. We...
متن کاملExpression of pendrin and the Pendred syndrome (PDS) gene in human thyroid tissues.
The gene recently cloned that is responsible for the Pendred syndrome (PDS), an autosomal recessive disease characterized by goiter and congenital sensorineural deafness, is mainly expressed in the thyroid gland. Its product, designated pendrin, was shown to transport chloride and iodide. To investigate whether the PDS gene is altered during thyroid tumorigenesis, PDS gene expression and pendri...
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Four patients are described in whom a follicular carcinoma developed following thyroidectomy for a benign follicular neoplasm. It is possible that the initial thyroid neoplasm was a well- differentiated follicular carcinoma which was microscopically indistinguishable from a benign adenoma. Realizing this pathologic pitfall in thyroid diagnosis, the need for meticulous examination of the pa...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2005
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6602628